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FAST LABEL-FREE METHOD FOR MAPPING CARDIAC PHYSIOLOGY
Researchers at The George Washington University are developing a fast label-free mapping system of excitation-contraction-metabolic waves at hundreds to thousands (e.g., 100-5,000) of frames per second for mapping cardica physiology. Such a system allows for clinical mapping of atrial and ventricular arrhythmia during, or prior to, ablation procedures...
Published: 1/11/2022
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Updated: 11/16/2021
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Inventor(s): Igor Efimov, Jaclyn Brennan
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology
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Intranasal Oxytocin Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a health risk that occurs in 24% of males and 9% of females in the United States. OSA can lead to several cardiovascular diseases including hypertension, arrhythmia, and stroke. Continuous positive airway pressure (CPAP) treatments often fail due to low compliance.
GW Researchers developed an intranasal oxytocin administration...
Published: 1/7/2022
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Updated: 11/4/2021
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Inventor(s): David Mendelowitz, Heather Jameson, Vivek Jain, Jay Kimbro
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Therapeutics > Proteins and Peptides
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Vital Ring: a Wearable Wireless Multiple-Lead ECG Sensor Embedded in a Flexible Finger Ring
Patients at risk of adverse cardiac events can benefit from mobile, on-demand, or real-time monitoring of their heart rhythms. Patient data can help diagnose symptoms of cardiac arrhythmias, heart attacks, and more. GW engineers incorporated advanced electrocardiogram (ECG) capabilities into a wearable device to provide portability and ease of use.
Competing...
Published: 1/7/2022
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Updated: 11/4/2021
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Inventor(s): Zhenyu Li, Quan Dong, Mona Zaghloul
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Diagnostic Devices, Technology Classifications > Medical Devices > Cardiology
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MitoScope: Minimally Invasive Device for Measuring the Energy Production Rate of Heart Tissue
The minimally invasive MitoScope assesses the metabolic rate of heart tissue in vivo, non-destructively, and in real-time. MitoScope measures the mitochondrial enzyme activity of the heart to provide unique insight that could improve the treatment of heart failure, coronary heart disease, diabetes, and many other diseases that alter myocardial metabolism....
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Matthew Kay, Angel Moreno, Rafael Jaimes, III
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology
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Thick 3D Bioprinted Cardiac Patch with Anisotropic and Perfusable Vessels
GW researchers fabricated a vascularized patch of cardiac tissue suitable for cardiac regeneration using 3D bioprinting. Cardiovascular disease involving myocardial infarction is a major cause of morbidity and mortality worldwide. Following myocardial infarction, adult cardiac tissue cannot significantly repair or regenerate itself. Current therapies...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology
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Therapeutics to prevent HIV-associated Coronary Artery Disease
HIV-infected patients have high risk of coronary artery disease (CAD). Previously, GW researchers identified HIV regulatory protein Nef as a causative factor in foam cell formation, a precursor condition to CAD. Currently, GW researchers developed compounds that show Nef-neutralizing effects in vitro. The prototype compounds restore cholesterol efflux...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Michael Bukrinsky, Ruth Hunegnaw, Alexei Adzhubei
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Therapeutics > Cells
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High-Throughput All-Optical Cardiac Electrophysiology System
The withdrawal of drugs from the market is a costly consequence of undetected adverse effects or toxicity. Over 30% of such withdrawals are due to cardiac toxicity (pro-arrhythmic effects mediated by cardiac ion channels), therefore regulatory agreements mandate the testing of all new drugs for cardiac liability.
GW researchers developed the first...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Emilia Entcheva, Aleksandra Klimas
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices
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