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High-Throughput All-Optical Cardiac Electrophysiology System

The withdrawal of drugs from the market is a costly consequence of undetected adverse effects or toxicity. Over 30% of such withdrawals are due to cardiac toxicity (pro-arrhythmic effects mediated by cardiac ion channels), therefore regulatory agreements mandate the testing of all new drugs for cardiac liability. GW researchers developed the first...

Published: 1/7/2022 | Updated: 10/14/2021 | Inventor(s): Emilia Entcheva, Aleksandra Klimas

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

Researchers at The George Washington University are developing innovative analytics for power grid online surveillance (event detection and classification with minimum latency) and real-time situational awareness. The novel analytics can be deployed as a stand-alone next-generation smart sensor or can be embedded within the existing phasor measurement...

Published: 1/7/2022 | Updated: 10/6/2021 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

3D Biophotonic Devices for All Optical Electrophysiology

Optical actuation and sensing methods were demonstrated by GW for high-throughput drug and cardiotoxicity screening. However, modification of target cells takes time, has variable yield and can cause potential interference with cell’s innate functional responses. GW researchers manufactured “spark-cell” spheroids, used as a reagent...

Published: 1/7/2022 | Updated: 9/29/2021 | Inventor(s): Emilia Entcheva, Christianne Chua

Keywords(s):

Category(s): Technology Classifications > Research Tools > Drug Screening