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Method to generate cold atmospheric plasma-stimulated media to treat cancer
For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics
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Magnetically Enhanced Plasma Treatment of Cancer
Previously, GW researchers invented a method to selectively kill cancer cells with cold atmospheric plasma (CAP), while leaving neighboring normal cells unaffected. In the present invention, the researchers devised an enhanced method for CAP cancer therapy by concurrently exposing the cancer cells to a static magnetic field (Fig. 1).
The researchers...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Michael Keidar, Xiaoqian Cheng, Alexey Shashurin, Jonathan Sherman
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics
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Optimization of Cold Atmospheric Plasma-Stimulated Media for Treatment of Cancer
Previously, GW researchers invented a method to selectively kill cancer cells with cold atmospheric plasma (CAP) while leaving neighboring normal cells intact. In a subsequent study, the researchers showed that similar anti-cancer effects can be achieved indirectly using CAP-stimulated media (CAPSM).
Stability of CAPSM (preservation of its anti-cancer...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Dayun Yan, Michael Keidar, Jonathan Sherman
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Proteins and Peptides, Technology Classifications > Therapeutics
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3D printed vascularized tissue scaffold with extracellular matrix triggered growth factor release
Vas-Scaf” is a 3D bio-printed vascularized bone scaffold perfused with osteogenic and angiogenic growth factors. Artificial bone grafts lacking vascularization fail due to poor integration of new tissues with the host and death of interior bone tissues. Bone and blood vessel tissues require different support structures and different biochemical...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Haitao Cui, Wei Zhu, Benjamin Holmes, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Nanoparticles, Technology Classifications > Industrial or Consumer Tech > Materials
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New Use for Small Molecule to Kill Malaria Parasites
GW researchers synthesized the new small molecule, RCB-185, and initially showed efficacy against Mycobacterium tuberculosis (Mtb), but now demonstrate much higher efficacy against malaria. According to the World Health Organization, 2015 had 212 million cases of malaria with 429,000 deaths. People desperately need new treatments for malaria, as use...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Cynthia Dowd, Robert Brothers, Audrey Odom, Rachel Edwards
Keywords(s):
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Small Molecules
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