Search Results - norman+lee

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Prostate Cancer Diagnostics and Therapeutics Based on Differential Gene Splicing
Many more African Americans (AA) die from prostate cancer than Caucasian Americans (CA), even after factoring in socioeconomic influences. The NIH designated identifying medically relevant differences in these populations as a high priority research area. Inventors at GWU identified differences in gene splicing between AA and CA prostate cancer samples....
Published: 1/7/2022   |   Updated: 11/13/2021   |   Inventor(s): Norman Lee, Steven Patierno, Bi-Dar Wang
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Therapeutics > RNA
Companion Diagnostics and Compound Screening Assay for PI3K Inhibitors
The phosphatidylinositol 3-kinase (PI3K) protein family regulates cellular functions including growth, proliferation, survival, differentiation, and motility. Because these functions are critical for cancer progression, many companies are developing therapeutic compounds to inhibit PI3K. GW inventors identified an alternative splicing variant of PIK3CD...
Published: 1/7/2022   |   Updated: 11/13/2021   |   Inventor(s): Norman Lee, Bi-Dar Wang, Steven Patierno
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides