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Prostate Cancer Diagnostics and Therapeutics Based on Differential Gene Splicing
Many more African Americans (AA) die from prostate cancer than Caucasian Americans (CA), even after factoring in socioeconomic influences. The NIH designated identifying medically relevant differences in these populations as a high priority research area. Inventors at GWU identified differences in gene splicing between AA and CA prostate cancer samples....
Published: 1/7/2022
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Updated: 11/13/2021
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Inventor(s): Norman Lee, Steven Patierno, Bi-Dar Wang
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Therapeutics > RNA
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Antisense RNA therapy for liver carcinoma
A GW researcher invented a nucleic acid based therapy for Hepatitis C Virus (HCV) infection associated hepatocellular carcinoma (HCC, liver cancer). Currently available antiviral drugs can only eliminate short term effects of the HCV. But liver damage, caused by chronic HCV infections, carries the very high risk of developing into hepatocellular carcinoma,...
Published: 1/7/2022
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Updated: 11/9/2021
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Inventor(s): Ajit Kumar, Nagarajan Pattabiraman
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Proteins and Peptides, Technology Classifications > Therapeutics > RNA
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Diagnostic method for detecting bacterial/viral infections by host RNA levels in blood
In instances of respiratory distress, it is often difficult to determine whether an infection is present or if the distress is purely inflammatory in nature. Treatments for these conditions differ greatly (either with antibiotics for infection or with anti-inflammatory drugs in case of no infection), although symptoms can often be similar. Currently,...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Timothy McCaffrey, Lakhmir Chawla
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > RNA
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