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Combining Dual 3D Bioprinting and Regional Bioactive Factors to Make Vascularized Bone Construct
GW researchers generated a vascularized and highly osteogenic bone construct with a biphasic structure using a multiple 3D printing platform. Traditional tissue engineering techniques face major obstacles in creating multiple tissue structures and vascularization of tissues. 3D bioprinting allows for control over the location of cells and biomaterials;...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Haitao Cui, Wei Zhu, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine
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Microbubble and Ultrasound Therapies to Enhance Cartilage Repair and Regrowth
By combining low intensity pulsed ultrasound (LIPUS) with lipid coated microbubbles, researchers at GW increased differentiation of human mesenchymal stem cells (hMSCs) into cartilage. Existing treatments for damaged cartilage include autografts, allografts, and total joint replacement. Autografts suffer from donor site morbidity and insufficient donor...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Kausik Sarkar, Mitra Aliabouzar, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine
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3D Printing Blood Vessels Without Sacrificial Templates
Using novel bioactive ink for 3D printing, GW researchers create multi-layered vasculature. Large-scale artificial tissue implants for defect reconstruction require vascularization to avoid interior necrosis, but blood vessel printing remains challenging.
Current 3D bioprinting methods for creating vasculature mainly utilize sacrificial templates to...
Published: 1/7/2022
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Updated: 10/14/2021
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Inventor(s): Haitao Cui, Lijie Zhang, Wei Zhu
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Industrial or Consumer Tech > Materials, Technology Classifications > Therapeutics > Cells
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