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In vitro drug treatment to proliferate and activate effector cells for immunotherapy
STAT5 SUMOylation inhibition increases CD4 and CD8 T-cell proliferation and and production of immune effector molecules in CD8 T-cells and NK (natural killer) cells. Both attributes address critical limiting factors in applying cell therapies to fighting cancers and pathogens. The difficulty of obtaining enough activated effector cells limits the...
Published: 1/7/2022
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Updated: 10/26/2021
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Inventor(s): Alberto Bosque-Pardos, Amanda Beatriz Rodrigues Barreto de Macedo, Eric Sorensen, Vicente Planelles
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Small Molecules
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